منابع مشابه
Developmental gene network analysis.
The developmental process is controlled by the information processing functions executed by the cis-elements that regulate the expression of the participating genes. A model of the network of cis-regulatory interactions that underlies the specification of the endomesoderm of the sea urchin embryo is analyzed here. Although not all the relevant interactions have yet been uncovered, the model sho...
متن کاملGene regulation: gene control network in development.
Controlling the differential expression of many thousands of genes is the most fundamental task of a developing organism. It requires an enormous computational device that has the capacity to process in parallel a vast number of regulatory inputs in the various cells of the embryo and come out with regulatory outputs that are tissue specific. The regulatory genome constitutes this computational...
متن کاملGene Network Biological Validity Based on Gene-Gene Interaction Relevance
In recent years, gene networks have become one of the most useful tools for modeling biological processes. Many inference gene network algorithms have been developed as techniques for extracting knowledge from gene expression data. Ensuring the reliability of the inferred gene relationships is a crucial task in any study in order to prove that the algorithms used are precise. Usually, this vali...
متن کاملPRRT2, a network stability gene
Specific paroxysmal disorders, namely benign infantile epilepsy (BFIE), kinesigenic dyskinesia (PKD), infantile convulsions and choreoathetosis (ICCA) and hemiplegic migraine (HM), are associated with mutations in the gene encoding for PRoline-Rich Transmembrane protein 2 (PRRT2; Figure 1A, 1B). PRRT2 is a neuronspecific protein expressed on neuronal membranes and at synapses, with a prevalent ...
متن کاملGene Expression vs. Network Attractors
Microarrays, RNA-Seq, and Gene Regulatory Networks (GRNs) are common tools used to study the regulatory mechanisms mediating the expression of the genes involved in the biological processes of a cell. Whereas microarrays and RNA-Seq provide a snapshot of the average expression of a set of genes of a population of cells, GRNs are used to model the dynamics of the regulatory dependencies among a ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Seibutsu Butsuri
سال: 2000
ISSN: 0582-4052,1347-4219
DOI: 10.2142/biophys.40.316